CHEMOTHERAPY
Online ISSN : 1884-5894
Print ISSN : 0009-3165
ISSN-L : 0009-3165
Sulfamethoxazole-Trimethoprim合剤の臨床検討
山作 房之輔武田 元薄田 芳丸庭山 冒俊川島 士郎木下 康民土田 亮渡部 信
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1973 年 21 巻 2 号 p. 313-316

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Sulfamethoxazole-trimethoprim combination product was used orally 4-8 tablets daily for 5-67 days, in 10 patients (empyema 1, pneumonia 2, acute pharyngitis 1, co-infection of pulmonary tuberculosis 1, lymphadenitis colli simplex 1, chronic pyelonephritis 1, cholecystitis 2, typhoid fever carrier 1).
(1) The results were excellent in 1 patient (empyema), good in 6 patients, fair in 1 patient (typhoid fever carrier), poor in 1 patient (lymphadenitis colli simplex) and uncertain (because of simultaneous use of CET) in 1 patient (pnenumonia).
(2) Side effects were observed in 4 patients, nausea 1, poor appetite 1, glossitis 1, skin rush, fever and iridocyclitis (maybe the side effects of sulfamethoxazole) 1.
(3) Two patients showed leucopenia, one became soon normal after the finish of the treatment, another became also normal in spite of using the drugs.
(4) No disturbance of liver and renal function was detected.

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