Blood Flow Changes In Transplantable Urothelial Tumors Treated With The Metallopurpurin, SnET2 And Light.

Steven H. Selman; Binsheng Qin; Harold R. James; Rick W. Keck; Greta M. Garbo; Alan R. Morgan

doi:10.1117/12.978001

13 June 1989 Blood Flow Changes In Transplantable Urothelial Tumors Treated With The Metallopurpurin, SnET2 And Light.

Steven H. Selman, Binsheng Qin, Harold R. James, Rick W. Keck, Greta M. Garbo, Alan R. Morgan

Proceedings Volume 1065, Photodynamic Therapy: Mechanisms; (1989) https://doi.org/10.1117/12.978001
Event: OE/LASE '89, 1989, Los Angeles, CA, United States

Abstract

Changes in blood flow to transplantable bladder tumors growing in Fischer rats were measured after photodynamic therapy with the photosensitizer tin (II) etiopurpurin dichloride (SnET2) using the radioactive microsphere technique. As with the other photosensitizers, hematoporphyrin derivative and chloroaluminum tetrasulfophthalocyanine, SnET2 and light caused a rapid decrease in tumor blood flow. This occurred when the vehicle for photosensitizer delivery was either an emulsion or a liposome. Systemic heparinization of animals did not alter changes in tumor blood flow.

Citation Download Citation

Steven H. Selman, Binsheng Qin, Harold R. James, Rick W. Keck, Greta M. Garbo, and Alan R. Morgan "Blood Flow Changes In Transplantable Urothelial Tumors Treated With The Metallopurpurin, SnET2 And Light.", Proc. SPIE 1065, Photodynamic Therapy: Mechanisms, (13 June 1989); https://doi.org/10.1117/12.978001

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available