Photothermal heating of optically trapped gold nanoparticles quantified using controlled vesicle cargo release

Anders Kyrsting; Poul M. Bendix; Lene B. Oddershede

doi:10.1117/12.930477

10 October 2012 Photothermal heating of optically trapped gold nanoparticles quantified using controlled vesicle cargo release

Anders Kyrsting, Poul M. Bendix, Lene B. Oddershede

Author Affiliations +

Proceedings Volume 8458, Optical Trapping and Optical Micromanipulation IX; 84580X (2012) https://doi.org/10.1117/12.930477
Event: SPIE NanoScience + Engineering, 2012, San Diego, California, United States

Abstract

Optically trapped metallic nanoparticles hold great promise as heat transducers in photothermal applications such as drug delivery assays or photothermal therapy. We use the heat dissipated from an optically trapped gold nanosphere to perform a controlled release of a fluorescently labeled vesicle lumen. In the assay, the ambient temperature is kept below the phase transition temperature of the vesicle. When the temperature reaches the phase transition temperature of the lipid, the vesicle becomes leaky and the fluorescently marked lumen diffuses out. We used gel phase vesicles as sensors to quantify the temperature profile around a nanoparticle optically trapped in three dimensions in a similar way as presented in Ref.¹ Trapping of 200 nm gold particles resulted in lower than expected heating, which may be accredited to the displacement of the particle from the optical focus due to high scattering forces experienced by the particle.

Citation Download Citation

Anders Kyrsting, Poul M. Bendix, and Lene B. Oddershede "Photothermal heating of optically trapped gold nanoparticles quantified using controlled vesicle cargo release", Proc. SPIE 8458, Optical Trapping and Optical Micromanipulation IX, 84580X (10 October 2012); https://doi.org/10.1117/12.930477

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available