Optical fiber biosensor based on enzymatic coating matrix for catecholamines assessment in human urine

Lurdes I. B. Silva; Ana C. Freitas; Teresa A. P. Rocha-Santos; M. E. Pereira; Armando C. Duarte

doi:10.1117/12.865820

8 September 2010 Optical fiber biosensor based on enzymatic coating matrix for catecholamines assessment in human urine

Lurdes I. B. Silva, Ana C. Freitas, Teresa A. P. Rocha-Santos, M. E. Pereira, Armando C. Duarte

Proceedings Volume 7653, Fourth European Workshop on Optical Fibre Sensors; 76531I (2010) https://doi.org/10.1117/12.865820
Event: (EWOFS'10) Fourth European Workshop on Optical Fibre Sensors, 2010, Porto, Portugal

Abstract

An optical fiber (OF) biosensor has been developed and applied for simultaneous determination of catecholamines (dopamine, norepinephrine and epinephrine) in human urine. The developed analytical device shows a high potential for catecholamines quantification with a detection limit of 2.1, 2.6 and 3.4 pg mL^-1 for dopamine, norepinephrine and epinephrine, respectively. The analytical performance of the OF biosensor was found to be similar to that of the High Performance Liquid Chromatography - Electrochemical Detector (HPLC-ED) regarding catecholamines determination in samples of human urine.

Citation Download Citation

Lurdes I. B. Silva, Ana C. Freitas, Teresa A. P. Rocha-Santos, M. E. Pereira, and Armando C. Duarte "Optical fiber biosensor based on enzymatic coating matrix for catecholamines assessment in human urine", Proc. SPIE 7653, Fourth European Workshop on Optical Fibre Sensors, 76531I (8 September 2010); https://doi.org/10.1117/12.865820

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