A dynamic micro-CT scanner with a stationary mouse bed using a compact carbon nanotube field emission x-ray tube

Guohua Cao; Xiomara Calderon-Colon; Peng Wang; Laurel Burk; Yueh Z. Lee; Ramya Rajaram; Shabana Sultana; David Lalush; Jianping Lu; Otto Zhou

doi:10.1117/12.813817

13 March 2009 A dynamic micro-CT scanner with a stationary mouse bed using a compact carbon nanotube field emission x-ray tube

Guohua Cao, Xiomara Calderon-Colon, Peng Wang, Laurel Burk, Yueh Z. Lee, Ramya Rajaram, Shabana Sultana, David Lalush, Jianping Lu, Otto Zhou

Author Affiliations +

Proceedings Volume 7258, Medical Imaging 2009: Physics of Medical Imaging; 72585Q (2009) https://doi.org/10.1117/12.813817
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

In this paper we report the development of a high resolution dynamic micro-computed tomography (CT) scanner with a stationary mouse bed using a compact carbon nanotube (CNT) x-ray tube. The scanner comprises a rotating x-ray tube and detector pair and a stationary and a horizontally positioned small animal bed. The system is optimized for in vivo mouse cardiac imaging. Its performance is evaluated with CT scans of phantoms and free-breathing mice. The modulation transfer function (MTF) at 10% is 5 lp/mm. At single frame acquisition, mouse cardiac micro-CT at 20msec temporal resolution has been demonstrated by prospectively gating the imaging acquisitions to both respiration and cardiac signals.

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Guohua Cao, Xiomara Calderon-Colon, Peng Wang, Laurel Burk, Yueh Z. Lee, Ramya Rajaram, Shabana Sultana, David Lalush, Jianping Lu, and Otto Zhou "A dynamic micro-CT scanner with a stationary mouse bed using a compact carbon nanotube field emission x-ray tube", Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72585Q (13 March 2009); https://doi.org/10.1117/12.813817

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