Angiofil: a novel radio-contrast agent for post-mortem micro-angiography

Silke Grabherr; Marco Dominietto; Lisa Yu; Valentin Djonov; Bert Müller; Sebastian Friess

doi:10.1117/12.792077

18 September 2008 Angiofil: a novel radio-contrast agent for post-mortem micro-angiography

Silke Grabherr, Marco Dominietto, Lisa Yu, Valentin Djonov, Bert Müller, Sebastian Friess

Proceedings Volume 7078, Developments in X-Ray Tomography VI; 70781O (2008) https://doi.org/10.1117/12.792077
Event: Optical Engineering + Applications, 2008, San Diego, California, United States

Abstract

The radio-contrast agent Angiofil has recently been developed to be predominantely applied in forensic medicine. Angiofil is a liquid radio-contrast agent based on iodine. Its viscosity is easy to adjust by the choice and the concentration of the solvent. Therefore, it is well suited for penetrating vessels of different diameters. The liquid Angiofil avoids the sedimentation of suspensions containing radio-opaque materials such as barium sulfate. The injection of Angiofil into the vascular system of mice post-mortem results in remarkable data showing the vascular trees of tissues and entire organs. Penetration into the surrounding tissue was not observed. Consequently, Angiofil has the potential to reach the performance of the established casting agent Microfil.

Citation Download Citation

Silke Grabherr, Marco Dominietto, Lisa Yu, Valentin Djonov, Bert Müller, and Sebastian Friess "Angiofil: a novel radio-contrast agent for post-mortem micro-angiography", Proc. SPIE 7078, Developments in X-Ray Tomography VI, 70781O (18 September 2008); https://doi.org/10.1117/12.792077

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