Spectral and imaging fluorescence analysis with ALA-induced protoporphyrin IX with the aim to increase the efficiency of bladder transurethral resections

Boris P. Matveev; Boris V. Kudashev M.D.; Boris V. Bukharkin; Alexander A. Stratonnikov; Natalya V. Kulenok; Victor B. Loschenov

doi:10.1117/12.413703

31 January 2001 Spectral and imaging fluorescence analysis with ALA-induced protoporphyrin IX with the aim to increase the efficiency of bladder transurethral resections

Boris P. Matveev, Boris V. Kudashev M.D., Boris V. Bukharkin, Alexander A. Stratonnikov, Natalya V. Kulenok, Victor B. Loschenov

Author Affiliations +

Proceedings Volume 4156, Clinical Lasers and Diagnostics; (2001) https://doi.org/10.1117/12.413703
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

Present work deals with diagnostics of bladder tumors with the use of 5-amino-levulinic acid (ALA) by means of fluorescence image analysis in blue light followed by spectral fluorescence analysis of biopsy samples taken from suspicious bladder sites. It was found that fluorescence intensity of benign formations is lower than that of tumors suggesting the possible increasing of specificity of diagnostics with the use of spectral analysis.

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Boris P. Matveev, Boris V. Kudashev M.D., Boris V. Bukharkin, Alexander A. Stratonnikov, Natalya V. Kulenok, and Victor B. Loschenov "Spectral and imaging fluorescence analysis with ALA-induced protoporphyrin IX with the aim to increase the efficiency of bladder transurethral resections", Proc. SPIE 4156, Clinical Lasers and Diagnostics, (31 January 2001); https://doi.org/10.1117/12.413703

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