Computational analysis of biological phenomena

Robert R. Goldberg; Michael R. Goldberg

doi:10.1117/12.360277

27 August 1999 Computational analysis of biological phenomena

Robert R. Goldberg, Michael R. Goldberg

Proceedings Volume 3836, Machine Vision Systems for Inspection and Metrology VIII; (1999) https://doi.org/10.1117/12.360277
Event: Photonics East '99, 1999, Boston, MA, United States

Abstract

A knowledge based system is proposed that will automate the segmentation process for embryonic organogenesis image data. Different methodologies will be incorporated that enable the accurate segmentation of image data based on the 'fingerprint' pattern of a particular cell staining. A novel technique integrates perceptual organization concepts to solve the shortcomings of the medial axis transform at the growing tips of branch structures. The system will then recover the underlying 3D object space axes of growth for two and 3D measurements. Also, perceptual organization groupings are formed by coalescing multiple lines in an image into one structure. These groupings can be described by junction analysis nomenclature and appear in different formations in different organs and at specific times in the development yielding significant biological meaning.

Citation Download Citation

Robert R. Goldberg and Michael R. Goldberg "Computational analysis of biological phenomena", Proc. SPIE 3836, Machine Vision Systems for Inspection and Metrology VIII, (27 August 1999); https://doi.org/10.1117/12.360277

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available