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13 March 2024 Development of tissue-mimicking phantoms for pulse oximetry
Anant Bhusal, Sandhya Vasudevan, Md Sadique Hasan, Masoud Farahmand, William C. Vogt, Sandy Weininger, Yu Chen, Joshua Pfefer
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Proceedings Volume PC12833, Design and Quality for Biomedical Technologies XVII; PC128330A (2024) https://doi.org/10.1117/12.3004468
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Point-of-care measurement of blood oxygen saturation is commonly performed using pulse oximetry-based methods, yet clinical evidence indicates that these devices may exhibit racial disparities in accuracy. We are working to develop tissue-mimicking phantoms for performance comparison and standardization of pulse oximeters. In this study, we have evaluated the use of standard silicone modified by reducing curing agent content to reduce material hardness to biologically relevant levels. A new silicone formulation was identified which provides low hardness without modification. Measurements of compliance – channel diameter as a function of fluid pressure – indicate that both materials have potential for use in pulse oximeter testing.
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Anant Bhusal, Sandhya Vasudevan, Md Sadique Hasan, Masoud Farahmand, William C. Vogt, Sandy Weininger, Yu Chen, and Joshua Pfefer "Development of tissue-mimicking phantoms for pulse oximetry", Proc. SPIE PC12833, Design and Quality for Biomedical Technologies XVII, PC128330A (13 March 2024); https://doi.org/10.1117/12.3004468
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KEYWORDS
Oximetry
Polydimethylsiloxane
Tissues
Microfluidics
Point-of-care devices
Standards development
Oximeters
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