Simultaneous imaging of shallow and deep tissues based on multi-line scanning

Naoshi Yoneyama; Sota Nakazawa; Kanta Iyanagi; Yusuke Tanihata; Ryotaro Mori; Manabu Machida; Gordon T. Kennedy; Anthony J. Durkin; Keiichiro Kagawa

doi:10.1117/12.3000865

12 March 2024 Simultaneous imaging of shallow and deep tissues based on multi-line scanning

Naoshi Yoneyama, Sota Nakazawa, Kanta Iyanagi, Yusuke Tanihata, Ryotaro Mori, Manabu Machida, Gordon T. Kennedy, Anthony J. Durkin, Keiichiro Kagawa

Author Affiliations +

Proceedings Volume 12816, Photonics in Dermatology and Plastic Surgery 2024; 1281608 (2024) https://doi.org/10.1117/12.3000865
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

We report a quantitative tissue imagining method that combines spatial frequency domain imaging (SFDI) and near-infrared spectroscopy (NIRS) by using an illumination of multiple scanned lines. SFDI is suitable for measuring superficial and shallow tissues (<a few mm) with sinusoidal or stripe illuminations while NIRS, that measures the points apart from a point illumination, is for deeper tissues (a few to tens mm). Our scheme performs these methods by one measurement and provide depth-dependent reflectance images for shallow and deep tissues. At every pixel, a series of the pixel values for all scanning steps is processed in two different ways: SFDI by fast Fourier transform and NIRS by finding the minimum value. We assembled a prototype system and measured a phantom and a human arm. The line pitch and wavelength were 10mm and 785nm, respectively. We obtained reflectance images from the 32 captured images using the SFDI processing for 0-0.4mm-1 and the NIRS processing for the line pitches of 0.625- 10mm. The images by SFDI for higher spatial frequencies depicted the shallower blood vessels. In those by NIRS, the contrast of the deeper blood vessels was enhanced for the larger line pitches.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Naoshi Yoneyama, Sota Nakazawa, Kanta Iyanagi, Yusuke Tanihata, Ryotaro Mori, Manabu Machida, Gordon T. Kennedy, Anthony J. Durkin, and Keiichiro Kagawa "Simultaneous imaging of shallow and deep tissues based on multi-line scanning", Proc. SPIE 12816, Photonics in Dermatology and Plastic Surgery 2024, 1281608 (12 March 2024); https://doi.org/10.1117/12.3000865

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