Lab-on-fiber optrodes based on all-dielectric fluorescence enhancing metasurfaces

H. Alhalaby; M. Principe; H. Zaraket; P. Vaiano; A. Aliberti; G. Quero; A. Crescitelli; V. Di Meo; E. Esposito; M. Consales; A. Cusano

doi:10.1117/12.2679369

23 May 2023 Lab-on-fiber optrodes based on all-dielectric fluorescence enhancing metasurfaces

H. Alhalaby, M. Principe, H. Zaraket, P. Vaiano, A. Aliberti, G. Quero, A. Crescitelli, V. Di Meo, E. Esposito, M. Consales, A. Cusano

Author Affiliations +

Proceedings Volume 12643, European Workshop on Optical Fibre Sensors (EWOFS 2023); 126431G (2023) https://doi.org/10.1117/12.2679369
Event: European Workshop on Optical Fibre Sensors (EWOFS 2023), 2023, Mons, Belgium

Abstract

The need for miniaturized biological sensors which can be easily integrated into medical needles and catheters for in vivo liquid biopsies with ever-increasing performances has stimulated the interest of researchers in Lab-on-Fiber (LOF) technology. In this framework, the integration of Metasurfaces (MSs) on the tip of the optical fiber (Optical Fiber Meta- Tip, OFMT) has represented a major breakthrough. Indeed, we showed that a suitably designed plasmonic OFMT biosensor significantly outperforms standard plasmonic ones due to the advanced light wave manipulation of MSs. Here, to further improve the sensing performances, we propose a novel class of LOF optrodes for labelled biosensing based on dielectric fluorescence enhancing OFMT. We envision a single fiber probe with integrated a Silicon MS on its tip as a light coupled substrate that illuminates the sample and simultaneously collects the enhanced emission from the dye molecules labeling the biological target. We present a numerical environment to compute the fluorescence enhancement factor collected by a multi-mode-fiber, when on its tip a Silicon MS is laid, consisting of an array of cylindrical nanoantennas. According to the numerical results, a suitable design of the dielectric MS allows for a fluorescence enhancement up to three orders of magnitudes. Moreover, a feasibility study is carried out to verify the possibility to fabricate the designed MSs on the termination of multimode optical fibers using electron beam lithography followed by reactive ion etching. This work provides the main guidelines for the development of advanced LOF devices based on the fluorescence enhancement for labeled biosensing.

Citation Download Citation

H. Alhalaby, M. Principe, H. Zaraket, P. Vaiano, A. Aliberti, G. Quero, A. Crescitelli, V. Di Meo, E. Esposito, M. Consales, and A. Cusano "Lab-on-fiber optrodes based on all-dielectric fluorescence enhancing metasurfaces", Proc. SPIE 12643, European Workshop on Optical Fibre Sensors (EWOFS 2023), 126431G (23 May 2023); https://doi.org/10.1117/12.2679369

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
4 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Fluorescence

Dielectrics

Optical fibers

Multimode fibers

Nanoantennas

Plasmonics

Quantum emitters

Show All Keywords

Keywords/Phrases

Search In:

Publication Years