In-vivo measuring of blood-flow changes using diffusing wave correlation techniques

Igor Victorovich Meglinski; David A. Boas; Arjun G. Yodh; Britton Chance

doi:10.1117/12.266252

11 February 1997 In-vivo measuring of blood-flow changes using diffusing wave correlation techniques

Igor Victorovich Meglinski, David A. Boas, Arjun G. Yodh, Britton Chance

Proceedings Volume 3053, Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies: International Workshop; (1997) https://doi.org/10.1117/12.266252
Event: International Workshop on Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies, 1996, Saratov, Russian Federation

Abstract

We have non-invasively measured in vivo blood flow changes using photon correlation spectroscopy with a simple correlation diffusion model to study and quantify blood flow in the human arm during cuff ischemia. The method utilizes the Doppler broadening of light that arises in a multiply scattering dynamic media, and is also responsive to changes in absorption and scattering coefficients. Our measurements clearly show blood flow changes with cuff pressures, including the hyperemic overshoot after cuff release, that qualitatively agree with the physiological behavior of the cardiovascular system. In this paper, we present our method, results and discuss the clinical relevance of our findings.

Citation Download Citation

Igor Victorovich Meglinski, David A. Boas, Arjun G. Yodh, and Britton Chance "In-vivo measuring of blood-flow changes using diffusing wave correlation techniques", Proc. SPIE 3053, Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies: International Workshop, (11 February 1997); https://doi.org/10.1117/12.266252

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