In vivo detection of esophageal dysplasia using a/LCI light scattering with OCT image guidance

Haoran Zhang; Julianna Bordas; Kengyeh K. Chu; Lama Moussa; Alondra Santiago; Swathi Eluri; Nicholas Shaheen; Adam Wax

doi:10.1117/12.2610486

3 March 2022 In vivo detection of esophageal dysplasia using a/LCI light scattering with OCT image guidance

Haoran Zhang, Julianna Bordas, Kengyeh K. Chu, Lama Moussa, Alondra Santiago, Swathi Eluri, Nicholas Shaheen, Adam Wax

Proceedings Volume PC11974, Biomedical Applications of Light Scattering XII; PC1197402 (2022) https://doi.org/10.1117/12.2610486
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

We present a dual-modality instrument that utilizes a paddle-shaped probe to conduct OCT imaging and a/LCI nuclear size measurements simultaneously to provide both structural and functional information in a single device during an endoscopic procedure. The probe is 3D printed using biocompatible material to deliver both modalities to the same location on the esophageal epithelium as a means to detect pre-cancerous tissues. We will present an update of our current clinical study at the University of North Carolina Center for Esophageal Diseases and Swallowing (UNC CEDAS) with a target of 40 total patients with and without esophageal dysplasia.

Conference Presentation

Citation Download Citation

Haoran Zhang, Julianna Bordas, Kengyeh K. Chu, Lama Moussa, Alondra Santiago, Swathi Eluri, Nicholas Shaheen, and Adam Wax "In vivo detection of esophageal dysplasia using a/LCI light scattering with OCT image guidance", Proc. SPIE PC11974, Biomedical Applications of Light Scattering XII, PC1197402 (3 March 2022); https://doi.org/10.1117/12.2610486

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