Sensitivity-enhanced localized surface plasmon resonance biosensing format dedicated for point-of-care testing tools

J. Hastanin; C. Lenaerts; K. Fleury-Frenette; A. Roobroeck; S. Desprez; A. Hastanin

doi:10.1117/12.2585299

12 April 2021 Sensitivity-enhanced localized surface plasmon resonance biosensing format dedicated for point-of-care testing tools

J. Hastanin, C. Lenaerts, K. Fleury-Frenette, A. Roobroeck, S. Desprez, A. Hastanin

Author Affiliations +

Proceedings Volume 11757, Smart Biomedical and Physiological Sensor Technology XVIII; 117570I (2021) https://doi.org/10.1117/12.2585299
Event: SPIE Defense + Commercial Sensing, 2021, Online Only

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Abstract

We report on the numerical and experimental study of the localized surface plasmon resonance (LSPR) spectroscopy of gold nanoparticles (NPs) structures at the frustrated total internal reflection (LSPR_TIR). The investigated NPs structures were manufactured using two different microfabrication methods: the nano-sphere lithography, and the original one, involving the direct pulse laser writing. The last technology, developed by our research team, provides powerful tools for flexible patterning of the multichannel biochip with array of LSPR probes. The obtained results demonstrate a significant improvement in the LSPR wavelength sensitivity to sample refractive index and, in addition, a relatively efficient conversion of the incident light wave polarization.

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J. Hastanin, C. Lenaerts, K. Fleury-Frenette, A. Roobroeck, S. Desprez, and A. Hastanin "Sensitivity-enhanced localized surface plasmon resonance biosensing format dedicated for point-of-care testing tools", Proc. SPIE 11757, Smart Biomedical and Physiological Sensor Technology XVIII, 117570I (12 April 2021); https://doi.org/10.1117/12.2585299

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