Equatorial sclera anisotropy measured using ultrasound elastography

Runze Li; Susannah Waxman; Yi Hua; Fengyi Fengyi Zhang; Yan Li; Yirui Zhu; Xuejun Qian; Zhongping Chen; Qifa Zhou; Ian A. Sigal

doi:10.1117/12.2583975

5 March 2021 Equatorial sclera anisotropy measured using ultrasound elastography

Runze Li, Susannah Waxman, Yi Hua, Fengyi Fengyi Zhang, Yan Li, Yirui Zhu, Xuejun Qian, Zhongping Chen, Qifa Zhou, Ian A. Sigal

Author Affiliations +

Proceedings Volume 11645, Optical Elastography and Tissue Biomechanics VIII; 116450Z (2021) https://doi.org/10.1117/12.2583975
Event: SPIE BiOS, 2021, Online Only

Abstract

We characterized the stiffness and anisotropy of the equatorial sclera and its dependence on intraocular pressure (IOP). Porcine eyes were tested using ultrasound elastography under IOP control. Shear waves were induced using a mechanical shaker, and an off-axis 17.8 MHz transducer used to track the wave propagation in the equatorial and anterior-posterior directions. Wave speed was measured and used to estimate directional Young’s moduli. Anisotropy was defined as the ratio of the equatorial moduli to the anterior-posterior moduli. Sclera was stiffer in the equatorial direction, with anisotropy decreasing with IOP, from, 5.1 at 10 mmHg to 3.7 at 30 mmHg.

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Runze Li, Susannah Waxman, Yi Hua, Fengyi Fengyi Zhang, Yan Li, Yirui Zhu, Xuejun Qian, Zhongping Chen, Qifa Zhou, and Ian A. Sigal "Equatorial sclera anisotropy measured using ultrasound elastography", Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 116450Z (5 March 2021); https://doi.org/10.1117/12.2583975

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