Presentation
5 March 2021 Assessing the connective tissue of the human tympanic membrane by PSOCT-based local retardation imaging
Svea Steuer, Jonas Golde, Steffen Oßmann, Lars Kirsten, Joseph Morgenstern, Matthias Bornitz, Marcus Neudert, Edmund Koch
Author Affiliations +
Abstract
Pathological alterations of the connective tissue, e.g. in succession of chronic otitis media, impair the acousto-mechanical function of the tympanic membrane (TM). Currently, none of the diagnostic techniques used in clinical practice assesses these tissue changes. By applying polarization-sensitive optical coherence tomography (PSOCT), a depth-resolved imaging technique providing additional tissue-specific contrast, local polarization changes of the fibrous layers of a human TM ex vivo were detected due to the birefringence of collagen fibers. Reconstructing and displaying local retardation from single-input PSOCT measurements enables to distinguish different tissue types which reveals the potential of PSOCT to extend conventional ENT diagnostics.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Svea Steuer, Jonas Golde, Steffen Oßmann, Lars Kirsten, Joseph Morgenstern, Matthias Bornitz, Marcus Neudert, and Edmund Koch "Assessing the connective tissue of the human tympanic membrane by PSOCT-based local retardation imaging", Proc. SPIE 11627, Photonic Therapeutics and Diagnostics in Dentistry, Head and Neck Surgery, and Otolaryngology, 1162704 (5 March 2021); https://doi.org/10.1117/12.2583216
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KEYWORDS
Connective tissue

Ear

Polarization

Tissues

Diagnostics

Optical coherence tomography

Optical fibers

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