Probing renal ischemia reperfusion-induced cardiac hypertrophy by a Raman spectroscopy

Marcela Carneiro-Ramos; Carolina Junho; Gabrielle Nepomuceno; Herculano Martinho

doi:10.1117/12.2583128

5 March 2021 Probing renal ischemia reperfusion-induced cardiac hypertrophy by a Raman spectroscopy

Marcela Carneiro-Ramos, Carolina Junho, Gabrielle Nepomuceno, Herculano Martinho

Proceedings Volume 11621, Diagnostic and Therapeutic Applications of Light in Cardiology 2021; 116210U (2021) https://doi.org/10.1117/12.2583128
Event: SPIE BiOS, 2021, Online Only

Conference Poster

Abstract

Renal failure is characterized by systemic inflammation that affects directly some organs like liver, lung and heart. Patients with renal insufficiency have a higher risk for developing cardiovascular diseases, representing 45% of the causes of death in patients undergoing hemodialysis. It is reported that unilateral renal ischemia/reperfusion is able to generate renal lesion, followed by systemic sterile inflammation, resulting in development of cardiac remodeling and hypertrophy. Considering that, the focus of this study was to investigate the cardiac remodeling induced by renal ischemia/reperfusion protocol using Fourier-Transform Raman Spectroscopy (FT-Raman) to probe molecular changes in mice.

Conference Presentation

Citation Download Citation

Marcela Carneiro-Ramos, Carolina Junho, Gabrielle Nepomuceno, and Herculano Martinho "Probing renal ischemia reperfusion-induced cardiac hypertrophy by a Raman spectroscopy", Proc. SPIE 11621, Diagnostic and Therapeutic Applications of Light in Cardiology 2021, 116210U (5 March 2021); https://doi.org/10.1117/12.2583128

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available