Differentiation of erythematous and post-inflammatory pigment changes in cutaneous chronic graft-versus-host disease by hyperspectral imaging

Inga Saknīte; Shinwho Kwun; Xiaoqi Liu; Kathy Zhang; Alexis Hood; Fuyao Chen; Lauri Kangas; Ari Kukkonen; Pirjo Kortteisto; Michael Byrne; Madan Jagasia; Eric R. Tkaczyk

doi:10.1117/12.2578532

5 March 2021 Differentiation of erythematous and post-inflammatory pigment changes in cutaneous chronic graft-versus-host disease by hyperspectral imaging

Inga Saknīte, Shinwho Kwun, Xiaoqi Liu, Kathy Zhang, Alexis Hood, Fuyao Chen, Lauri Kangas, Ari Kukkonen, Pirjo Kortteisto, Michael Byrne, Madan Jagasia, Eric R. Tkaczyk

Author Affiliations +

Proceedings Volume 11618, Photonics in Dermatology and Plastic Surgery 2021; 116180J (2021) https://doi.org/10.1117/12.2578532
Event: SPIE BiOS, 2021, Online Only

Abstract

Through vertex component analysis of hyperspectral imaging data in the visible spectral range, we differentiated erythematous and pigmented areas in patients with cutaneous chronic graft-versus-host disease. We explored the feasibility of hyperspectral imaging in combination with unsupervised learning algorithms to differentiate active disease from inactive post-inflammatory skin changes, a fundamental practice gap in caring for these patients. We compared erythema and pigment maps to the visual assessment by a dermatologist as the ground truth.

Conference Presentation

Citation Download Citation

Inga Saknīte, Shinwho Kwun, Xiaoqi Liu, Kathy Zhang, Alexis Hood, Fuyao Chen, Lauri Kangas, Ari Kukkonen, Pirjo Kortteisto, Michael Byrne, Madan Jagasia, and Eric R. Tkaczyk "Differentiation of erythematous and post-inflammatory pigment changes in cutaneous chronic graft-versus-host disease by hyperspectral imaging", Proc. SPIE 11618, Photonics in Dermatology and Plastic Surgery 2021, 116180J (5 March 2021); https://doi.org/10.1117/12.2578532

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available