Presentation + Paper
10 March 2020 Towards reduced-preparation spectral-CT-colonography utilizing local covariance
Rafael Wiemker, Tobias Klinder, Jörg Sabczynski, Amar Dhanantwari, Chansik An, Benjamin M. Yeh, Judy Yee
Author Affiliations +
Abstract
In CT colonography (CTC), residual stool is a possible confounder in the detection of colonic polyps. While there is a clear clinical need for reduced or minimal bowel preparation for CT colonography, residual stool that is poorly tagged by oral contrast agent prevents satisfactory electronic cleansing (EC) by standard methods on conventional CT. Our study aims to answer quantitatively whether dual-layer spectral-CT allows superior discrimination of residual stool. 60 spectral CT colonography scans were obtained in clinical practice, and careful exhaustive ground truth was established by consensus reading.

Results indicate that spectral CT adds significant discrimination power, in particular when utilizing local spectral variances and covariances, which can be computed efficiently by standard Gaussian filter operations. Simple linear spectral material separation, however, is sufficient only in extended homogeneous regions. In subtle finely structured transition areas, non-linear classifiers or convolutional neural networks are required because of non-linear local multi material superposition effects.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Rafael Wiemker, Tobias Klinder, Jörg Sabczynski, Amar Dhanantwari, Chansik An, Benjamin M. Yeh, and Judy Yee "Towards reduced-preparation spectral-CT-colonography utilizing local covariance", Proc. SPIE 11313, Medical Imaging 2020: Image Processing, 113130I (10 March 2020); https://doi.org/10.1117/12.2549539
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CITATIONS
Cited by 2 patents.
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KEYWORDS
Colon

Computed tomography

Virtual colonoscopy

Convolutional neural networks

CT reconstruction

Colorectal cancer

Medicine

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