Fieldable, real-time enzyme immunoassay kits for drugs on surfaces

Michele Weber Chiappini; Gregory J. Wendel; Peter H. Duquette; Martha J. Hamilton; Stephen J. Chudzik; Ralph A. Chappa

doi:10.1117/12.171240

28 March 1994 Fieldable, real-time enzyme immunoassay kits for drugs on surfaces

Michele Weber Chiappini, Gregory J. Wendel, Peter H. Duquette, Martha J. Hamilton, Stephen J. Chudzik, Ralph A. Chappa

Proceedings Volume 2092, Substance Detection Systems; (1994) https://doi.org/10.1117/12.171240
Event: Substance Identification Technologies, 1993, Innsbruck, Austria

Abstract

Immunoassays (e.g., RIA, EIA) have been demonstrated to be useful for rapid, convenient detection and semiquantitative analysis of drugs. Thermedics Detection, Inc. manufactures a rapid, sensitive, self-contained, disposable, EIA device, developed by Bio-Metric Systems, Inc., designed to allow untrained personnel to perform in field situations. This format has been developed for drugs in biological fluids and on surfaces. The analyte in the test sample competes with an enzyme-analyte conjugate for a limited number of immobilized antibody sites. The AccuPRESS Test format can detect analytes at 10 ppb in biological fluids, water, and soil, and on surfaces, such as suitcases, vehicles, tables and hands, with positive results indicated by clearly visible color development within 5 minutes. This format is designed to have all dry components and to have an ambient shelf life of greater than one year. The format is available for cocaine and opiate derivatives, including heroin, and is readily adaptable for use with numerous other drugs, explosives, and environmental pollutants.

Citation Download Citation

Michele Weber Chiappini, Gregory J. Wendel, Peter H. Duquette, Martha J. Hamilton, Stephen J. Chudzik, and Ralph A. Chappa "Fieldable, real-time enzyme immunoassay kits for drugs on surfaces", Proc. SPIE 2092, Substance Detection Systems, (28 March 1994); https://doi.org/10.1117/12.171240

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