A palliative relief of cholestasis was successfully achieved by a continuous PTCD in two patients of biliary atresia who had undergone an unsuccessful Kasai procedure. A temporary impovement in liver functions was observed by decompression of iatrahepatic biliary system. Irrigation of the infected bile ducts was effective for management of cholangitis. Determinations of the antibiotic levels in the bile have provided a fact that a damaged liver does not transfer the systemically given antibiotics into the bile. These two patients finally died of progressive liver damage. However, a continuous PTCD seemed to be useful for preparation of future liver transplantation in such patients.