Kansenshogaku Zasshi
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
A Case of Report-Interferon Therapy is Useful for Chronic Hepatitis C with Human Immunodefficiency Virus Infection
Kazumi YAMASHITAJun HAYASHITetsuro YAMAMOTOYondo PEIKazuhiro ISESeizaburo KASHIWAGI
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JOURNAL FREE ACCESS

1998 Volume 72 Issue 6 Pages 647-650

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Abstract

A 42-year-old male type A hemophiliae who been using coagulates since 1971 was diagnosed Human Immunodefficiency Virus (HIV) positive in 1993. Medical history included liver disfunction in 1987, with chronic hepatitis C (CHC) diagnosed in 1989. He was admitted to the hospital in October, 1994 because of general fatigue. Serum transaminase was elevated, CD4 was 221/micro L, and CD8 was 990. CD4/CD8 ratio was 0.2. HCV was of genotype 2b and 106 copies/50 micro L. 8-week-Interferon (IFN)-β-treatment was started. HCV RNA was eliminated by week 8 and was sustained for one year with no severe side effects. With caerful patient screening, IFN therapy for CHC with HIV may be an effective treatment.

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© The Japansese Association for Infectious Diseases
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