1988 Volume 62 Issue 7 Pages 623-627
Adherence of gram negative bacilli to normal and mechanical injured rat tracheas was examined. Rat tracheas were injured by endotracheal intubation and balooning for 2 hours with Swan Ganz catheter, and they were incubated with P. aeruginosa, K pneumoniae and E. coli. All of the three strains were suspended at 2×107 CFU/ml for the experiment. All of them adhered more to the injured tracheas than to normal tracheas, and the adherence of P. aeruginosa was especially high. These data were similar to the data of acid injured rat tracheas.
Rat tracheal mucin was preincubated with all the three strains and the adherence of mucin treated bacteria to mechanical injured tracheas was examined. Mucin inhibited the adherence of P. aeruginosa. This suggested that P. aeruginosa adhered to tracheal mucin very well.
