Recently, China has taken steps to open up its international air transport services at a higher level during its 14th Five-Year Period. As one step, a number of pilot free trade zones (PFTZs) have been launched with different tasks for foreign economic cooperation based on institutional innovation. Some cities in these zones have been chosen to develop airport economy by liberalization of the fifth freedom traffic right (FFTR). Considering the different economic situations between passenger and cargo market following the outbreak of the coronavirus, this chapter focuses on its implication of the FFTR for air cargo and airport economy in these cities. Some air service agreements (ASAs) between China and other countries have contained the arrangements on the FFTR. However, this study argues that such arrangements are too general and need further negotiation and policy support for practical utilization. FFTR liberalization may drive cargo growth and economic development in the cities which have gained such policy support, but it may also bring competitive pressure on Chinese airlines. Furthermore, the FFTR liberalization policies do not guarantee an immediate positive result in fostering airport economy, and much work is needed for better utilization of the FFTR in China.