1887

Abstract

Rift Valley fever (RVF) is caused by infection with Rift Valley fever virus (RVFV), a mosquito-borne RNA virus that affects both humans and livestock species. Humans can also acquire infection from contact with infected animals and contaminated bodily fluid. Veterinary vaccines are available for use in livestock, but no vaccines have been approved for humans to date. The virus is currently endemic in most sub-Saharan regions of Africa but numerous incursions into Middle Eastern countries and islands in the Indian Ocean, such as Mayotte (an overseas Department of France), have occurred in the past decade. The risk of further geographical expansion is high and therefore additional investigation is warranted to better understand disease transmission and pathogenic mechanisms to develop threat mitigation strategies.

Funding
This study was supported by the:
  • Department for Environment, Food and Rural Affairs, UK Government (Award SV3045)
    • Principle Award Recipient: NicholasJohnson
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
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/content/journal/jmm/10.1099/jmm.0.001619
2022-12-16
2024-04-27
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References

  1. Daubney R, Hudson JR, Garnham PC. Enzootic hepatitis or Rift Valley fever. An undescribed virus disease of sheep cattle and man from east africa. J Pathol 1931; 34:545–579 [View Article]
    [Google Scholar]
  2. Samy AM, Peterson AT, Hall M. Phylogeography of Rift Valley fever virus in Africa and the Arabian Peninsula. PLoS Negl Trop Dis 2017; 11:e0005226 [View Article]
    [Google Scholar]
  3. Javelle E, Lesueur A, Pommier de Santi V, de Laval F, Lefebvre T et al. The challenging management of rift valley fever in humans: literature review of the clinical disease and algorithm proposal. Ann Clin Microbiol Antimicrob 2020; 19(1):4
    [Google Scholar]
  4. Odendaal L, Davis AS, Venter EH. Insights into the pathogenesis of viral haemorrhagic fever based on virus tropism and tissue lesions of natural Rift Valley fever. Viruses 2021; 13:709 [View Article]
    [Google Scholar]
  5. Boshra H, Lorenzo G, Busquets N, Brun A. Rift valley fever: recent insights into pathogenesis and prevention. J Virol 2011; 85:6098–6105 [View Article] [PubMed]
    [Google Scholar]
  6. Maluleke MR, Phosiwa M, van Schalkwyk A, Michuki G, Lubisi BA et al. A comparative genome analysis of Rift Valley fever virus isolates from foci of the disease outbreak in South Africa in 2008-2010. PLOS Negl Trop Dis 2019; 13:e0006576 [View Article]
    [Google Scholar]
  7. Shiell BJ, Ye S, Harper JA, van der Heide B, Beddome G et al. Reagents for detection of Rift Valley fever virus infection in sheep. J Vet Diagn Invest 2020; 32:577–580 [View Article] [PubMed]
    [Google Scholar]
  8. Mansfield KL, Banyard AC, McElhinney L, Johnson N, Horton DL et al. Rift Valley fever virus: a review of diagnosis and vaccination, and implications for emergence in Europe. Vaccine 2015; 33:5520–5531 [View Article]
    [Google Scholar]
  9. Petrova V, Kristiansen P, Norheim G, Yimer SA. Rift Valley fever: diagnostic challenges and investment needs for vaccine development. BMJ Glob Health 2020; 5:e002694 [View Article]
    [Google Scholar]
  10. Smithburn KC, Mahaffy AF et al. Rift valley fever; accidental infections among laboratory workers. J immunol 1949; 62:213–227
    [Google Scholar]
  11. Lorenzo G, López-Gil E, Warimwe GM, Brun A. Understanding Rift Valley fever: contributions of animal models to disease characterization and control. Mol Immunol 2015; 66:78–88 [View Article] [PubMed]
    [Google Scholar]
  12. Lumley S, Horton DL, Hernandez-Triana LLM, Johnson N, Fooks AR et al. Rift Valley fever virus: strategies for maintenance, survival and vertical transmission in mosquitoes. J Gen Virol 2017; 98:875–887 [View Article] [PubMed]
    [Google Scholar]
  13. Lichoti JK, Kihara A, Oriko AA, Okutoyi LA, Wauna JO et al. Detection of Rift Valley fever virus interepidemic activity in some hotspot areas of kenya by sentinel animal surveillance, 2009-2012. Vet Med Int 2014:379010 [View Article]
    [Google Scholar]
  14. Jansen van Vuren P, Shalekoff S, Grobbelaar AA, Archer BN, Thomas J et al. Serum levels of inflammatory cytokines in Rift Valley fever patients are indicative of severe disease. Virol J 2015; 12:159 [View Article]
    [Google Scholar]
  15. Bird BH, Albariño CG, Hartman AL, Erickson BR, Ksiazek TG et al. Rift valley fever virus lacking the NSs and NSm genes is highly attenuated, confers protective immunity from virulent virus challenge, and allows for differential identification of infected and vaccinated animals. J Virol 2008; 82:2681–2691 [View Article] [PubMed]
    [Google Scholar]
  16. Bron GM, Strimbu K, Cecilia H, Lerch A, Moore SM et al. Over 100 years of Rift Valley fever: a patchwork of data on pathogen spread and spillover. Pathogens 2021; 10:708 [View Article]
    [Google Scholar]
  17. Anyangu AS, Gould LH, Sharif SK, Nguku PM, Omolo JO et al. Risk factors for severe Rift Valley fever infection in Kenya, 2007. Am J Trop Med Hyg 2010; 83:14–21 [View Article] [PubMed]
    [Google Scholar]
  18. Tigoi C, Sang R, Chepkorir E, Orindi B, Arum SO et al. High risk for human exposure to Rift Valley fever virus in communities living along livestock movement routes: a cross-sectional survey in Kenya. PLoS Negl Trop Dis 2020; 14:e0007979 [View Article]
    [Google Scholar]
  19. Nyakarahuka L, de St Maurice A, Purpura L, Ervin E, Balinandi S et al. Prevalence and risk factors of Rift Valley fever in humans and animals from Kabale district in Southwestern Uganda, 2016. PLOS Negl Trop Dis 2018; 12:e0006412 [View Article]
    [Google Scholar]
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