Thermoresponsive swelling of photoacoustic single-chain nanoparticles

Justus F. Thümmler; Ramesh Maragani; Franz-Josef Schmitt; Guo Tang; Samira Mahmoudi Rahmanlou; Jan Laufer; Henrike Lucas; Karsten Mäder; Wolfgang H. Binder

doi:10.1039/D3CC03851C

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Thermoresponsive swelling of photoacoustic single-chain nanoparticles†

Justus F. Thümmler,

^a Ramesh Maragani,

^a Franz-Josef Schmitt,

^b Guo Tang,

^b Samira Mahmoudi Rahmanlou,

^b Jan Laufer,

^b Henrike Lucas,^c Karsten Mäder^c and Wolfgang H. Binder

*^a

Author affiliations

* Corresponding authors

^a Institute of Chemistry, Faculty of Natural Sciences II, Martin Luther University Halle-Wittenberg, von-Danckelmann-Platz 4, Halle D-06120, Germany
E-mail: wolfgang.binder@chemie.uni-halle.de

^b Institute of Physics, Faculty of Natural Sciences II, Martin Luther University Halle-Wittenberg, von-Danckelmann-Platz 3, Halle D-06120, Germany

^c Institute of Pharmacy, Faculty of Natural Sciences I, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 3, Halle D-06120, Germany

Abstract

NIR-fluorescent LCST-type single-chain nanoparticles (SCNPs) change their photophysical behaviour upon heating, caused by depletion of water from the swollen SCNP interiors. This thermoresponsive effect leads to a fluctuating photoacoustic (PA) signal which can be used as a contrast mechanism for PA imaging.

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Article information

DOI: https://doi.org/10.1039/D3CC03851C
Article type: Communication
Submitted: 09 Aug 2023
Accepted: 23 Aug 2023
First published: 30 Aug 2023

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Chem. Commun., 2023,59, 11373-11376

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Thermoresponsive swelling of photoacoustic single-chain nanoparticles

J. F. Thümmler, R. Maragani, F. Schmitt, G. Tang, S. M. Rahmanlou, J. Laufer, H. Lucas, K. Mäder and W. H. Binder, Chem. Commun., 2023, 59, 11373 DOI: 10.1039/D3CC03851C

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Chemical Communications

Thermoresponsive swelling of photoacoustic single-chain nanoparticles†

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Thermoresponsive swelling of photoacoustic single-chain nanoparticles

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