Issue 21, 2023
From the journal:

Chemical Communications

Molecularly imprinted and cladded polymers for constructing a portable plasmonic immunoassay for peptides in biofluids†

Zhanchen Guo,‡a   Qi Zhang,‡a   Rongrong Xinga  and  Zhen Liu ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
E-mail: zhenliu@nju.edu.cn

Abstract

Using two molecularly imprinted and cladded polymers (cMIPs), an inexpensive, fast and portable plasmonic immuno-sandwich assay (PISA) was rationally developed for high-specificity and ultra-sensitive detection of C-peptide in urine. The dual cMIPs-based PISA allowed healthy individuals to be distinguished from diabetes patients and exhibited several significant merits over existing immunoassays, holding great promise in clinical diagnosis.

Graphical abstract: Molecularly imprinted and cladded polymers for constructing a portable plasmonic immunoassay for peptides in biofluids

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Article information

DOI
https://doi.org/10.1039/D2CC06550A
Article type
Communication
Submitted
01 Dec 2022
Accepted
09 Feb 2023
First published
10 Feb 2023

Chem. Commun., 2023,59, 3075-3078

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Molecularly imprinted and cladded polymers for constructing a portable plasmonic immunoassay for peptides in biofluids

Z. Guo, Q. Zhang, R. Xing and Z. Liu, Chem. Commun., 2023, 59, 3075 DOI: 10.1039/D2CC06550A

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