Issue 74, 2022
From the journal:

Chemical Communications

A nanoplatform for mild-temperature photothermal and type I & II photodynamic therapy in the NIR-II biowindow†

Bing Lu, ORCID logo *a   Zhecheng Zhang,a   Yuying Huang,a   Yuehua Zhang,a   Jin Wang,a   Yue Ding, ORCID logo a   Yang Wang ORCID logo a  and  Yong Yao ORCID logo *a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Nantong University, Nantong, Jiangsu, P. R. China
E-mail: 2020028lubing@ntu.edu.cn, yaoyong1986@ntu.edu.cn

Abstract

In the current work, we synthesized an A–D–A smallmolecule photosensitizer, denoted as DPTTIC, and a dual PEG-functionalized pillararene, denoted as WP5-8C-2PEG, and used them to construct novel DPTTIC nanoparticles (NPs) displaying NIR II absorption. Under 980 nm-wavelength laser irradiation, DPTTIC NPs performed well in mild-temperature photothermal and type I & II photodynamic anti-tumor therapy.

Graphical abstract: A nanoplatform for mild-temperature photothermal and type I & II photodynamic therapy in the NIR-II biowindow

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Article information

DOI
https://doi.org/10.1039/D2CC03248A
Article type
Communication
Submitted
09 Jun 2022
Accepted
18 Aug 2022
First published
18 Aug 2022

Chem. Commun., 2022,58, 10353-10356

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A nanoplatform for mild-temperature photothermal and type I & II photodynamic therapy in the NIR-II biowindow

B. Lu, Z. Zhang, Y. Huang, Y. Zhang, J. Wang, Y. Ding, Y. Wang and Y. Yao, Chem. Commun., 2022, 58, 10353 DOI: 10.1039/D2CC03248A

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