Issue 54, 2022
From the journal:

Chemical Communications

Photoelectrochemical bioanalysis of microRNA on yolk-in-shell Au@CdS based on the catalytic hairpin assembly-mediated CRISPR-Cas12a system†

Ruijin Zeng,‡a   Jianhui Xu,‡a   Liling Lu,a   Qianyun Lin,a   Xue Huang,a   Lingting Huang,a   Meijin Li ORCID logo *a  and  Dianping Tang ORCID logo *a  

* Corresponding authors

a Key Laboratory for Analytical Science of Food Safety and Biology (MOE & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China
E-mail: mjli@fzu.edu.cn, dianping.tang@fzu.edu.cn

Abstract

This work reports on the proof-of-concept of a photoelectrochemical (PEC) biosensor with a horseradish peroxidase-single stranded DNA-encoded magnetic bead (MB-ssDNA-HRP) signal probe cleaved by the catalytic hairpin assembly (CHA)-mediated clustered regularly interspaced short palindromic repeats (CRISPR)-Cas12a system for the quantification of microRNA (miR-21) by using yolk-in-shell Au@CdS as a photoactive material.

Graphical abstract: Photoelectrochemical bioanalysis of microRNA on yolk-in-shell Au@CdS based on the catalytic hairpin assembly-mediated CRISPR-Cas12a system

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D2CC02821B
Article type
Communication
Submitted
18 May 2022
Accepted
09 Jun 2022
First published
09 Jun 2022

Chem. Commun., 2022,58, 7562-7565

Permissions

Request permissions

Photoelectrochemical bioanalysis of microRNA on yolk-in-shell Au@CdS based on the catalytic hairpin assembly-mediated CRISPR-Cas12a system

R. Zeng, J. Xu, L. Lu, Q. Lin, X. Huang, L. Huang, M. Li and D. Tang, Chem. Commun., 2022, 58, 7562 DOI: 10.1039/D2CC02821B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements