Issue 24, 2021
From the journal:

Organic Chemistry Frontiers

Access to azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition with exclusive regioselectivity†

Yin Liu,‡ab   Yicheng He,‡b   Yang Liu,b   Kun Weia  and  Wusheng Guo ORCID logo *bc  

* Corresponding authors

a School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China

b Frontier Institute of Science and Technology (FIST), Xi'an Jiaotong University, Xi'an 710045, China
E-mail: wusheng.guo@mail.xjtu.edu.cn

c School of Chemistry, Xi'an Key Laboratory of Sustainable Energy Materials Chemistry, and MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, Xi'an Jiaotong University, Xi'an 710049, China

Abstract

A highly efficient approach for the synthesis of azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition has been developed. This procedure utilizes methylene cyclic carbonates as a C5-dipole and 1-azadiene as a C4-synthon. The reactions could be performed at room temperature. The protocol features wide functional group tolerance with exclusive regioselectivity and generates CO2 as the only byproduct.

Graphical abstract: Access to azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition with exclusive regioselectivity

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D1QO01405F
Article type
Research Article
Submitted
18 Sep 2021
Accepted
28 Oct 2021
First published
30 Oct 2021

Org. Chem. Front., 2021,8, 7004-7008

Permissions

Request permissions

Access to azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition with exclusive regioselectivity

Y. Liu, Y. He, Y. Liu, K. Wei and W. Guo, Org. Chem. Front., 2021, 8, 7004 DOI: 10.1039/D1QO01405F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements