Issue 6, 2022
From the journal:

Organic & Biomolecular Chemistry

NHC-catalyzed [4 + 2] annulations of allenoates and 2,3-dioxopyrrolidine derivatives†

Xue Song,a   Yangxu Chen,a   Fangfang Lu,a   Kai Zhang, ORCID logo *a   Chenxia Yu,a   Tuanjie Li*a  and  Changsheng Yao ORCID logo *a  

* Corresponding authors

a School of Chemistry and Materials Science, Jiangsu Key Lab of Green Synthetic Chemistry for Functional Materials. Jiangsu Normal University, Xuzhou, Jiangsu 221116, P. R. China
E-mail: csyao@jsnu.edu.cn

Abstract

A facile NHC-catalyzed [2 + 4] annulation of allenoates with 2,3-dioxypyrrolidine derivatives was discovered, which paved a new avenue for the construction of highly substituted pyranopyrrole with moderate to good yields, high atom economy and mild reaction conditions.

Graphical abstract: NHC-catalyzed [4 + 2] annulations of allenoates and 2,3-dioxopyrrolidine derivatives

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Article information

DOI
https://doi.org/10.1039/D1OB02180J
Article type
Paper
Submitted
07 Nov 2021
Accepted
07 Jan 2022
First published
08 Jan 2022

Org. Biomol. Chem., 2022,20, 1219-1225

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NHC-catalyzed [4 + 2] annulations of allenoates and 2,3-dioxopyrrolidine derivatives

X. Song, Y. Chen, F. Lu, K. Zhang, C. Yu, T. Li and C. Yao, Org. Biomol. Chem., 2022, 20, 1219 DOI: 10.1039/D1OB02180J

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