Issue 35, 2019
From the journal:

Organic & Biomolecular Chemistry

Palladium-catalyzed multicomponent reactions: an overview

Salim Saranya,a   K. R. Rohit,a   Sankaran Radhikaa  and  Gopinathan Anilkumar ORCID logo *ab  

* Corresponding authors

a School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P O, Kottayam, Kerala 686 560, India
E-mail: anilgi1@yahoo.com

b Advanced Molecular Materials Research Centre (AMMRC), Mahatma Gandhi University, Priyadarsini Hills P O, Kottayam, Kerala 686 560, India

Abstract

This first review on this topic focuses on the developments in the chemistry of Pd-catalyzed multi-component reactions (MCRs). MCRs are generally atom economic, ideal and eco-friendly reactions, and often the final products are generated almost without any by-products. In this review, the developments in Pd-catalyzed MCRs are categorized based on the products formed such as acyclic compounds, carbocyclic compounds, heterocyclic compounds and miscellaneous compounds. MCRs have great applications in various fields like medicinal chemistry, combinatorial synthesis, heterocyclic chemistry etc. and this review covers the literature up to 2019.

Graphical abstract: Palladium-catalyzed multicomponent reactions: an overview

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Article information

DOI
https://doi.org/10.1039/C9OB01538H
Article type
Review Article
Submitted
11 Jul 2019
Accepted
07 Aug 2019
First published
07 Aug 2019

Org. Biomol. Chem., 2019,17, 8048-8061

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Palladium-catalyzed multicomponent reactions: an overview

S. Saranya, K. R. Rohit, S. Radhika and G. Anilkumar, Org. Biomol. Chem., 2019, 17, 8048 DOI: 10.1039/C9OB01538H

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