Issue 61, 2015
From the journal:

Chemical Communications

A novel deep photodynamic therapy modality combined with CT imaging established via X-ray stimulated silica-modified lanthanide scintillating nanoparticles†

Ahmed H. Elmenoufy,‡ab   Yong'an Tang,‡a   Jun Hu,*a   Huibi Xua  and  Xiangliang Yang*a  

* Corresponding authors

a National Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China
E-mail: hjun0718@163.com, nanomedicine@mail.hust.edu.cn
Fax: +86-27-87792234
Tel: +86-27-87793539

b Department of Pharmaceutical Chemistry, College of Pharmacy, Misr University for Science and Technology, P.O. Box: 77, Al-Motamayez District, 6th of October City, Egypt

Abstract

Multifunctional LaF3:Tb scintillating nanoparticles (ScNPs) coated with homogenous layers of silica and subsequently tethered with RB covalently were elaborated. The nanoconjugates with a high colloidal stability and biocompatibility could generate a reasonable amount of 1O2 through efficient energy transfer upon external illumination, which enables them to be potentially applied in diagnosis and photodynamic therapy for deep seated tumour.

Graphical abstract: A novel deep photodynamic therapy modality combined with CT imaging established via X-ray stimulated silica-modified lanthanide scintillating nanoparticles

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Article information

DOI
https://doi.org/10.1039/C5CC04135J
Article type
Communication
Submitted
19 May 2015
Accepted
19 Jun 2015
First published
19 Jun 2015

Chem. Commun., 2015,51, 12247-12250

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A novel deep photodynamic therapy modality combined with CT imaging established via X-ray stimulated silica-modified lanthanide scintillating nanoparticles

A. H. Elmenoufy, Y. Tang, J. Hu, H. Xu and X. Yang, Chem. Commun., 2015, 51, 12247 DOI: 10.1039/C5CC04135J

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