Issue 90, 2014
From the journal:

Chemical Communications

Subphthalocyanines: addressing water-solubility, nano-encapsulation, and activation for optical imaging of B16 melanoma cells†

Yann Bernhard,a   Pascale Winckler,b   Remi Chassagnon,c   Philippe Richard,a   Élodie Gigot,a   Jean-Marie Perrier-Cornetb  and  Richard A. Decréau*a  

* Corresponding authors

a Institut de Chimie Moléculaire de l'Université de Bourgogne (ICMUB), UMR 6302 CNRS – Université de Bourgogne, BP 47870, Dijon Cedex, France
E-mail: Richard.Decreau@u-bourgogne.fr

b Université de Bourgogne, AgroSup Dijon, Dimacell Imaging Ressource Center, UMR A 02.102 PAM, F-21000 Dijon, France

c Laboratoire Interdisciplinaire Carnot Bourgogne, UMR CNRS 6303 – Université de Bourgogne, F-21078 Dijon, France

Abstract

Water-soluble disulfonato-subphthalocyanines (SubPcs) or hydrophobic nano-encapsulated SubPcs are efficient probes for the fluorescence imaging of cells. 20 nm large liposomes (TEM and DLS) incorporated about 13% SubPc. Moreover, some of these fluorophores were found to be pH activatable.

Graphical abstract: Subphthalocyanines: addressing water-solubility, nano-encapsulation, and activation for optical imaging of B16 melanoma cells

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Article information

DOI
https://doi.org/10.1039/C4CC05503A
Article type
Communication
Submitted
16 Jul 2014
Accepted
15 Sep 2014
First published
16 Sep 2014

Chem. Commun., 2014,50, 13975-13978

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Subphthalocyanines: addressing water-solubility, nano-encapsulation, and activation for optical imaging of B16 melanoma cells

Y. Bernhard, P. Winckler, R. Chassagnon, P. Richard, É. Gigot, J. Perrier-Cornet and R. A. Decréau, Chem. Commun., 2014, 50, 13975 DOI: 10.1039/C4CC05503A

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