Issue 5, 2009
From the journal:

Chemical Communications

Dynamic kinetic resolution of β-keto sulfonesvia asymmetric transfer hydrogenation†

Zhenhua Ding,a   Jin Yang,a   Ting Wang,a   Zongxuan Shena  and  Yawen Zhang*a  

* Corresponding authors

a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Soochow University, Suzhou, China
E-mail: zhangyw@suda.edu.cn
Fax: +86-0512-65880305
Tel: +86-0512-65880340

Abstract

The dynamic kinetic resolution of β-keto sulfones was achieved via asymmetric transfer hydrogenation using (S,S)-RuCl[N-(tosyl)-1,2-diphenylethylenediamine](p-cymene) in the presence of formic acid and triethylamine afforded the desired products in good yield with up to >99 : 1 dr and high ee up to >99%.

Graphical abstract: Dynamic kinetic resolution of β-keto sulfones via asymmetric transfer hydrogenation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B818257D
Article type
Communication
Submitted
20 Oct 2008
Accepted
26 Nov 2008
First published
19 Dec 2008

Chem. Commun., 2009, 571-573

Permissions

Request permissions

Dynamic kinetic resolution of β-keto sulfones via asymmetric transfer hydrogenation

Z. Ding, J. Yang, T. Wang, Z. Shen and Y. Zhang, Chem. Commun., 2009, 571 DOI: 10.1039/B818257D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements