Issue 11, 2008
From the journal:

Chemical Communications

Conjugated polyelectrolyte–DNA complexes for multi-color and one-tube SNP genotyping assays†

Xinrui Duan,a   Shu Wang*a  and  Zhengping Li*b  

* Corresponding authors

a Beijing National Laboratory for Molecular Science, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, P. R. China
E-mail: wangshu@iccas.ac.cn
Fax: +86 10 6263 6680
Tel: +86 10 6263 6680

b College of Chemistry and Environmental Science, Hebei University, Hebei Province, P. R. China
E-mail: lzpbd@mail.hbu.edu.cn

Abstract

The complexes of a cationic conjugated polymer with DNA are designed as new platforms for homogeneous, sensitive and facile fluorescence assays for SNP genotyping, which interface with single-base extension, multi-step FRET and optical amplification properties of conjugated polymers.

Graphical abstract: Conjugated polyelectrolyte–DNA complexes for multi-color and one-tube SNP genotyping assays

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Article information

DOI
https://doi.org/10.1039/B717300H
Article type
Communication
Submitted
08 Nov 2007
Accepted
26 Dec 2007
First published
23 Jan 2008

Chem. Commun., 2008, 1302-1304

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Conjugated polyelectrolyte–DNA complexes for multi-color and one-tube SNP genotyping assays

X. Duan, S. Wang and Z. Li, Chem. Commun., 2008, 1302 DOI: 10.1039/B717300H

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