Issue 21, 2005

The synthesis and directed ortho-lithiation of 4-tert-butylsulfinyl[2.2]paracyclophane

Abstract

The ortho-lithiation of one diastereoisomer of 4-tert-butylsulfinyl[2.2]paracyclophane is the key step to the synthesis of a range of 4,5-disubstituted [2.2]paracyclophane derivatives.

Graphical abstract: The synthesis and directed ortho-lithiation of 4-tert-butylsulfinyl[2.2]paracyclophane

Supplementary files

Article information

Article type
Communication
Submitted
14 Jul 2005
Accepted
07 Sep 2005
First published
26 Sep 2005

Org. Biomol. Chem., 2005,3, 3873-3876

The synthesis and directed ortho-lithiation of 4-tert-butylsulfinyl[2.2]paracyclophane

P. B. Hitchcock, G. J. Rowlands and R. J. Seacome, Org. Biomol. Chem., 2005, 3, 3873 DOI: 10.1039/B509994C

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