Issue 5, 2001
From the journal:

Chemical Society Reviews

Synthetic models of cation-conducting channels

George W. Gokel*a  and  Anindita Mukhopadhyaya  

* Corresponding authors

a Bioorganic Chemistry Program and Dept. of Molecular Biology & Pharmacology, Washington University School of Medicine, 660 S. Euclid Ave., Campus Box 8103, St. Louis, USA

Abstract

Modern channel proteins are complex in structure and marvelous in function. The earliest channels cannot possibly have been so complex but they must have functioned at some modest level. Synthetic chemists have designed a variety of novel structures with the goal of creating a mimic of channel function that is complex enough to function in a bilayer but simple enough to be understood, dissected, and modified. These synthetic model systems are the subject of this article.

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Article information

DOI
https://doi.org/10.1039/B008667N
Article type
Review Article
Submitted
15 May 2001
First published
24 Aug 2001

Chem. Soc. Rev., 2001,30, 274-286

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Synthetic models of cation-conducting channels

G. W. Gokel and A. Mukhopadhyay, Chem. Soc. Rev., 2001, 30, 274 DOI: 10.1039/B008667N

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