Abstract
IN previous reports from this laboratory it was noted that two or more sex chromatin bodies are present in some female nuclei, particularly in those from amnion epithelium1–3. Barr and Moore4 found multiple sex chromatin in some nuclei from malignant tumours and suggested that this is due to hyper-ploidy. Myers5 described multiple sex chromatin in teratomas. Atkin6 found that 7 out of 65 malignant tumours from females had two sex chromatin-like bodies per nucleus. He assumed that these nuclei were tetraploid and confirmed this with the aid of chromosome counts and estimations of deoxyribonucleic acid. It was of interest to determine if in non-pathological tissue the female nuclei in which we had found more than one sex chromatin body were of a polyploid nature and whether the occasional sex chromatin-like structure in male nuclei could be correlated with polyploidy.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Klinger, H. P., Acta Anat., 30, 371 (1957).
Klinger, H. P., and Ludwig, K. S., Z. Anat. Entw. Gesch., 120, 95 (1957).
Klinger, H. P., Exp. Cell Res., 14, 207 (1958).
Barr, M. L., and Moore, K. L., Canadian Cancer Conference, 2, 3 (Academic Press, Inc., 1956).
Myers, L., Symposium on Nuclear Sex, London, Sept. 6–7, 1957 (Proceedings in the press).
Atkin, N. B. (same as ref. 5).
Klinger, H. P., and Ludwig, K. S., Stain Technol., 32, 235 (1957).
Graham, M. A., and Barr, M. L., Anat. Rec., 112, 709 (1952).
Moore, K. L., and Barr, M. L., J. Comp. Neurol., 98, 213 (1953).
Bassermann, F. J., Aerztl. Wschr., 12, 307 (1957).
Klinger, H. P. (same as ref. 5).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KLINGER, H., SCHWARZACHER, H. Sex Chromatin in Polyploid Nuclei of Human Amnion Epithelium. Nature 181, 1150–1152 (1958). https://doi.org/10.1038/1811150a0
Issue Date:
DOI: https://doi.org/10.1038/1811150a0
This article is cited by
-
Amnion-derived pluripotent/multipotent stem cells
Stem Cell Reviews (2006)
-
Heterochromatin, repetitive DNS und Nukleolen in Leberzellen von Microtus agrestis
Histochemie (1972)
-
Intermitotic transformation of the Barr body in cultured cells of the human female
Zeitschrift für Zellforschung und Mikroskopische Anatomie (1964)
-
Origin of Placental Trophoblast
Nature (1960)
-
Observations on the so-called sex chromatin
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie (1960)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.