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Analysis of pathogens and antimicrobial treatment in different groups of patients with chronic otitis media

Published online by Cambridge University Press:  27 October 2021

W Kaźmierczak ,
J Janiak-Kiszka ,
A Budzyńska ,
M Nowaczewska ,
H Kaźmierczak  and
E Gospodarek-Komkowska
W Kaźmierczak
Affiliation:
Department of Human Physiology, Collegium Medicum Nicolaus Copernicus University, Bydgoszcz, Poland
J Janiak-Kiszka
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, and Laryngological Oncology, Faculty of Medicine, Collegium Medicum Nicolaus Copernicus University, Bydgoszcz, Poland
A Budzyńska
Affiliation:
Department of Microbiology, Faculty of Pharmacy, Collegium Medicum Nicolaus Copernicus University, Bydgoszcz, Poland
M Nowaczewska*
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, and Laryngological Oncology, Faculty of Medicine, Collegium Medicum Nicolaus Copernicus University, Bydgoszcz, Poland
H Kaźmierczak
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, and Laryngological Oncology, Faculty of Medicine, Collegium Medicum Nicolaus Copernicus University, Bydgoszcz, Poland
E Gospodarek-Komkowska
Affiliation:
Department of Microbiology, Faculty of Pharmacy, Collegium Medicum Nicolaus Copernicus University, Bydgoszcz, Poland
*
Author for correspondence: Dr M Nowaczewska, Department of Otolaryngology, Head and Neck Surgery, and Laryngological Oncology, Faculty of Medicine, Collegium Medicum Nicolaus Copernicus University, M. Skłodowskiej, Curie number 9, 85-094 Bydgoszcz, Poland E-mail: magy_mat@by.onet.pl
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Abstract

Objective

Microbial infection plays an important role in exacerbation of chronic otitis media. The aim of this study was to analyse the microbiota in chronic otitis media in the context of local treatment.

Method

In this prospective study, samples for microbiological examination were taken from 119 patients who underwent operation because of chronic otitis media.

Results

The results were compared between groups depending on the type of operation (none, tympanoplasty or radical), the presence of cholesteatoma or granulomatous tissue or discharge from the ear as a symptom of exacerbation. Antibiotic susceptibility of germs was analysed to define the strategy of treatment. A total of 209 samples were collected from 119 patients with chronic otitis media.

Conclusion

Pseudomonas aeruginosa and Staphylococcus aureus were pathogens most frequently identified from the ear in the course of chronic otitis media. Pseudomonas aeruginosa was concerned with major pathology of the middle ear (radical surgery, cholesteatoma or granulomatous tissue, persisting discharge after treatment), whereas Staphylococcus aureus was obtained in dry perforations without other pathology in the middle-ear cavity. Ciprofloxacin was effective against Staphylococcus aureus, but Pseudomonas aeruginosa strains were ciprofloxacin resistant.

Keywords

MicrobiotaChronic Otitis MediaTympanoplastyAntibiotics
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 136 , Issue 3 , March 2022 , pp. 219 - 222
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED.

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Footnotes

Dr M Nowaczewska takes responsibility for the integrity of the content of the paper

References

Ricciardiello, F, Cavaliere, M, Mesolella, M, Iengo, M. Notes on the microbiology of cholesteatoma: clinical findings and treatment. Acta Otorhinolaryngol Ital 2009;29:197–202Google ScholarPubMed
European Committee on Antimicrobial Susceptibility Testing. In: www.eucast.org/clinical_breakpoints/ [27 December 2021]Google Scholar
Wysocki, J, Bartoszewicz, R. Safety of topical ear medication in different clinical situations. Pol Przegl Otorynolar 2013;2:86–92Google Scholar
Vishwanath, S, Mukhopadhyay, C, Prakash, R, Pillai, S, Pujary, K, Pujary, P. Chronic suppurative otitis media: optimizing initial antibiotic therapy in a tertiary care setup. Indian J Otolaryngol Head Neck Surg 2012;64:285–9CrossRefGoogle Scholar
Dayasena, R, Dayasiri, M, Jayasuriya, C, Perera, D. Aetiological agents in chronic suppurative otitis media in Sri Lanka. Australas Med J 2011;4:101–4Google ScholarPubMed
Blakley, BW, Kim, S. Does chronic otitis media cause sensorineural hearing loss? J Otolaryngol 1998;27:17–20Google ScholarPubMed
Haynes, DS, Rutka, J, Hawke, M, Roland, PS. Ototoxicity of ototopical drops--an update. Otolaryngol Clin North Am 2007;40:669–83CrossRefGoogle ScholarPubMed
Niemczyk, K, Bartoszewicz, R. Otorrhea-management algorithm. Pol Przegl Otolaryngol 2013;2:15–20Google Scholar
Mozafari Nia, K, Sepehri, G, Khatmi, H, Shakibaie, MR. Isolation and antimicrobial susceptibility of bacteria from chronic suppurative otitis media patients in Kerman, Iran. Iran Red Crescent Med J 2011;13:891–4Google ScholarPubMed
Dzierżanowska, D. Mechanisms of quinolone resistance in pathogens responsible for infections in the outpatient clinic. Lekarz POZ 2017;3:425–1Google Scholar
Song, JJ, Lee, BD, Lee, KH, Lee, JD, Park, YJ, Park, MK. Changes in antibiotic resistance in recurrent Pseudomonas aeruginosa infections of chronic suppurative otitis media. Ear Nose Throat J 2016;95:446–51CrossRefGoogle ScholarPubMed
Vennewald, I, Klemm, E. Otomycosis: diagnosis and treatment. Clin Dermatol 2010;28:202–11CrossRefGoogle ScholarPubMed
Tom, LW. Ototoxicity of common topical antimycotic preparations. Laryngoscope 2000;110:509–16CrossRefGoogle ScholarPubMed
Dohar, J, Giles, W, Roland, P, Bikhazi, N, Carroll, S, Moe, R et al. Topical ciprofloxacin/dexamethasone superior to oral amoxicillin/clavulanic acid in acute otitis media with otorrhea through tympanostomy tubes. Pediatrics 2006;118:561–9CrossRefGoogle ScholarPubMed