Hostname: page-component-76fb5796d-qxdb6 Total loading time: 0 Render date: 2024-04-26T01:36:36.163Z Has data issue: false hasContentIssue false
  • English
  • Français

Immunogenetics of a macroglobulin allotype in cattle

Published online by Cambridge University Press:  14 April 2009

Domenico Iannelli  and
Piero Masina
Domenico Iannelli
Affiliation:
Institute of Animal Production, University of Naples
Piero Masina
Affiliation:
Institute of Animal Production, University of Naples
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The paper describes a cattle serum antigen (McA2) located on a macroglobulin molecule which has its isoelectric point at pH 5 and is capable of interacting with the wheat germ lectin and concanavalin A.

The specificity is inherited in a simple Mendelian manner and the gene controlling its synthesis is allelic to the one controlling the synthesis of the McAl antigen.

Type
Research Article
Information
Genetics Research , Volume 31 , Issue 3 , June 1978 , pp. 265 - 271
Copyright
Copyright © Cambridge University Press 1978

References

REFERENCES

Baglioni, C., Zonta, L. A., Cioli, D. & Carbonara, A. (1966). Allelic antigen factor Inv(a) of the light chains of human immunoglobulins: chemical basis. Science 152, 1517–1519.CrossRefGoogle ScholarPubMed
Berne, B. H., Dray, S. & Knight, K. L. (1970). Identification and genetic control of the Mt-3 and Mt-4 allotypes of rabbit serum α2-macroglobulin. Journal of Immunology 105, 856–864.CrossRefGoogle Scholar
Berne, B. H., Dray, S. & Knight, K. L. (1972). Contribution of the allelic Mtz3 and Mtz4 allotype genes to the formation of individual rabbit serum α2-macroglobulin molecules. Biochemical Genetics 7, 95–110.CrossRefGoogle Scholar
Butler, J. E. (1969). Bovine immunoglobulin. A review. Journal of Dairy Science 52, 1895–1909.CrossRefGoogle Scholar
Blakeslee, D., Butler, J. E. & Stone, W. H. (1971). Serum antigens of cattle. II. Immunogenetics of two immunoglobulin allotypes. Journal of Immunology 107, 227–235.CrossRefGoogle ScholarPubMed
Blakeselee, D., Rapacz, J. & Butler, J. E. (1971). Bovine immunoglobulin allotypes. Journal of Dairy Science 54, 1319–1320.Google Scholar
Fahey, J. L. & Terry, E. W. (1967). Ion exchange chromatography and gel filtration. In Handbook of Experimental Immunology pp. 19–43. Oxford: Blackwell.Google Scholar
Giblett, E. R. (1969). Genetic Markers in Human Blood. Oxford: Blackwell.Google Scholar
Golstein, I. J., Hammarström, S. & Sundblad, G. (1975). Precipitation and carbohydratebinding specificity studies on wheat germ agglutinin. Biochemical and Biophysical Acta 405, 56–61.Google Scholar
Golstein, I. J. & Iyer, B. N. (1966). Interaction of concanavalin A, a phytohemagglutinin, with model substrates. Biochemical and Biophysical Acta 121, 197–200.CrossRefGoogle Scholar
Iannelli, D. (1969). A serum antigen detected in cattle by micro-immuno-diffusion Experientia 25, 423.CrossRefGoogle ScholarPubMed
Iastnelli, D. (1974). Gruppi sanguigni ed allotipi nel bufalo (Bubalus Bubalis). In Atti del 1° Convegno Internazionale sull' Allevamento Bufalino nel Mondo, Caserta 1974, pp. 101–113.Google Scholar
Iannelli, D. (1978). Immunogeneties of a sheep (Ovis aries) serum antigen. Genetical Research 31, 209–213.CrossRefGoogle Scholar
Iantstelli, D., Masina, P. & Zacchi, B. (1968). Un antigene identificato nel siero dei bovini mediante isoprecipitine. Produzione Animale 7, 101–106.Google Scholar
Iannelli, D., Obeste, U., Masina, P., De Benedictis, G. & Cianfriglia, M. (1977). Genetics of a low density lipoprotein allotype in cattle. Animal Blood Groups and Biochemical Genetics (in the Press).Google Scholar
Josephson, R. V., Mikolajick, E. M. & Sinha, D. P. (1972). Gel isoelectric focusing of selected bovine immunoglobulins. Journal of Dairy Science 55, 1508–1510.CrossRefGoogle ScholarPubMed
Kunkel, H. G. (1960). Macroglobulin and high molecular weight antibodies. In The Plasma Proteins (ed. Putnam, F. W.), vol. I, pp. 279–307. New York and London: Academic Press.CrossRefGoogle Scholar
Morgan, W. T. J. (1960). A contribution to human biochemical genetics; the chemical basis of blood-group specificity. Proceedings of Royal Society B 151, 308–347.Google ScholarPubMed
Rapacz, J., Korda, N. & Stone, W. H. (1968). Serum antigens of cattle. I. Immunogenetics of a macroglobulin allotype. Genetics 58, 387–398.CrossRefGoogle ScholarPubMed
Rapacz, J., Korda, N. & Stone, W. H. (1975). Serum antigens of cattle. IV. Immunogenetics of a soluble antigenic determinant derived from lysed erythrocytes. Genetics 80, 323–329.CrossRefGoogle ScholarPubMed
Watkins, W. M. (1966). Blood group substances. Science 152, 172–181.CrossRefGoogle ScholarPubMed