The truth of the work, as determined by its origin in personal existence, is fully revealed and realized only through interpretation by other individuals reading it in relation to their own existence in the course of a history of reception. The Vita nuova can stand as emblematic of this process and as illustrative of its exceptionally fecund results in literary history. Often touted as the first book of Italian literary tradition, the Vita nuova is a seed of the very process of a literary tradition disseminating itself through ongoing production of works as responses such as Dante himself elicits in circulating the sonnet about his initiatory dream to fellow poets. Especially revealing of the history of effects of this text are its artistic appropriations at various periods in the iconographical tradition. The Pre-Raphaelite depictions, notably by Dante Gabriel Rossetti, illustrate how subjectively driven interpretation can become relevant to revealing the original, but temporally unbounded meaning of a text. Rossetti’s, like Dante’s, personal preoccupations prove instrumental for disclosing and illuminating what can be lived as perennial and perduring truths about human existence.