Hostname: page-component-848d4c4894-ttngx Total loading time: 0 Render date: 2024-06-03T07:58:01.773Z Has data issue: false hasContentIssue false
  • English
  • Français

Seroprevalence of toxoplasma gondii in Romanian psychiatric patients

Published online by Cambridge University Press:  23 March 2020

T.R. Olariu ,
I.D. Capraru ,
I. Papava ,
R. Romosan ,
L. Dehelean  and
M.A. Lupu
T.R. Olariu
Affiliation:
University of Medicine and Pharmacy “Victor Babes”, Parasitology, Timisoara, Romania
I.D. Capraru
Affiliation:
University of Medicine and Pharmacy “Victor Babes”, Parasitology, Timisoara, Romania
I. Papava
Affiliation:
University of Medicine and Pharmacy “Victor Babes”, Department of Neurosciences, Discipline of Psychiatry, Timisoara, Romania
R. Romosan
Affiliation:
University of Medicine and Pharmacy “Victor Babes”, Department of Neurosciences, Discipline of Psychiatry, Timisoara, Romania
L. Dehelean
Affiliation:
University of Medicine and Pharmacy “Victor Babes”, Department of Neurosciences, Discipline of Psychiatry, Timisoara, Romania
M.A. Lupu
Affiliation:
University of Medicine and Pharmacy “Victor Babes”, Parasitology, Timisoara, Romania

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Introduction

Toxoplasma gondii infection has been recently associated with schizophrenia and other psychiatric disorders.

Aim

The aim of the present study was to evaluate the prevalence of T. gondii antibodies among acute psychiatric patients from Western Romania.

Methods

This study included 214 consecutive patients admitted at the psychiatric clinic, Country Clinical Emergency Hospital in Timisoara, Romania, between 30.06.2011 and 12.01.2012. Clinical and laboratory investigations were performed in these hospitalized patients, including serologic tests for T. gondii IgG and IgM antibodies.

Results

The 214 patients aged 19 to 71 years (mean = 42.5), 64.9% were females. T. gondii antibodies were detected in 117 (54.7%) of 214 psychiatric patients. When the data were analyzed by diagnostic groups, T. gondii antibodies were demonstrated in 30 (50.84%) of 59 patients with schizophrenia, in 28 (59.57%) of 47 with persistent delusional disorder, 10 (31.25%) of 32 with acute and transient psychotic disorder, 13 (54.16%) of 24 with schizoaffective disorder and 35 (70%) of 50 with bipolar disorder. A high prevalence of T. gondii antibodies was found among patients with bipolar disorder compared to those with schizophrenia (P = 0.043) acute and transient psychotic disorder (P < 0.0001) and healthy controls (P < 0.0001). Of the 18 patients with schizophrenia and a BPRS score <51, T. gondii antibodies were detected in 13 (72.2%) compared to 17 (41.4%) of 41 in whom BPRS score was >51 (P = 0.03).

Conclusion

These findings suggest that T. gondii infection may be associated with several psychiatric disorders. A high seroprevalence of T. gondii was demonstrated in patients with bipolar disorder.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-Poster Viewing: Schizophrenia and other psychotic disorders
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. s825
Copyright
Copyright © European Psychiatric Association 2017
Submit a response

Comments

No Comments have been published for this article.