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Emerging role of MicroRNA-Based theranostics in Hepatocellular Carcinoma

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Abstract

Hepatocellular carcinoma (HCC), with its high mortality and short survival rate, continues to be one of the deadliest malignancies despite relentless efforts and several technological advances. The poor prognosis of HCC and the few available treatments are to blame for the low survival rate, which emphasizes the importance of creating new, effective diagnostic markers and innovative therapy strategies. In-depth research is being done on the potent biomarker miRNAs, a special class of non-coding RNA and has shown encouraging results in the early identification and treatment of HCC in order to find more viable and successful therapeutics for the disease. It is beyond dispute that miRNAs control cell differentiation, proliferation, and survival and, depending on the genes they target, can either promote tumorigenesis or suppress it. Given the vital role miRNAs play in the biological system and their potential to serve as ground-breaking treatments for HCC, more study is required to fully examine their theranostic potential.

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The authors declare that [the/all other] data supporting the findings of this study are available within the article.

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Acknowledgements

We would like to express our thanks to Mr. Abdulaziz Umar Kurya for his relentless efforts towards the english proofreading of our manuscript.

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  1. Department of Biomedical Engineering, Shobhit institute of Engineering and Technology (Deemed to-be-University), Modipuram, Meerut, 250110, India

    Abdulhakim Umar Toro & Sudheesh K. Shukla

  2. University Centre of Excellence in Research, Baba Farid University of Health Sciences, Faridkot, 151203, India

    Parveen Bansal

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  1. Abdulhakim Umar Toro
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Toro, A.U., Shukla, S.K. & Bansal, P. Emerging role of MicroRNA-Based theranostics in Hepatocellular Carcinoma. Mol Biol Rep 50, 7681–7691 (2023). https://doi.org/10.1007/s11033-023-08586-z

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