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Detection and Imaging of Small Molecules of Biological Significance

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Introduction to Fluorescence Sensing

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Abstract

Small biology-related molecules that are neutral or without a high charge density require special methods for their detection that will be highlighted in the present chapter. Due to small strength and number of potential contacts with the sensor, molecular recognition may not be very efficient, and their detection can be based on chemodosimetry concept. Many of these compounds possess specific reactivity that is the basis of their function, and this reactivity can be used to chemically modify the sensor for providing analytical signal. Here, the basic principles in the design of such sensors and the construction of smart molecular sensors and nanosensors that are able to detect multiple analytes is discussed.

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  1. National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry, Kyiv, Ukraine

    Alexander P. Demchenko

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Demchenko, A.P. (2023). Detection and Imaging of Small Molecules of Biological Significance. In: Introduction to Fluorescence Sensing. Springer, Cham. https://doi.org/10.1007/978-3-031-19089-6_10

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