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Principles for the Design of PET Probes

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Principles of Molecular Probe Design and Applications

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Abstract

This chapter will cover the knowledge of how to generate positron emitters and label them onto active pharmaceutical compounds ranging from small organic molecules to peptides and antibodies. The discussion will cover several mechanisms to improve the art of PET chemistry in a pedagogical approach. Labeling methods for [18F], [11C], [64Cu], and [68Ga] will be discussed, followed by practical examples in each case.

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Pham, W. (2023). Principles for the Design of PET Probes. In: Principles of Molecular Probe Design and Applications. Springer, Singapore. https://doi.org/10.1007/978-981-19-5739-0_3

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