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Choline chloride–based deep eutectic solvents (Ch-DESs) as promising green solvents for phenolic compounds extraction from bioresources: state-of-the-art, prospects, and challenges

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Abstract

As the demand for phenolic compounds in pharmaceutical, food, nutraceutical, and cosmetic production is escalating, recovery of phenolic compounds from bioresources has been receiving great concerns from the scientific community. Renewable, environmentally benign, and biocompatible choline chloride–based deep eutectic solvents (Ch-DESs) are considered potential alternatives to conventional solvents in phenolic compound extraction. In the past 2 years, numerous innovative studies centered on phenolic compound extraction using Ch-DESs and process variable optimization have been explored. Thus, this review aims to summarize the updated state-of-the-art effort dedicated to phenolic compounds extraction from various bioresources using Ch-DESs. Furthermore, impact factors, kinetic modeling, and chemical mechanisms of the process are thoroughly analyzed and discussed. Finally, prospects and challenges in commercialization of phenolic compound extraction from bioresources using Ch-DESs are indicated and extensively discussed.

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Acknowledgments

The authors are thankful for the valuable comments by anonymous reviewers, which help greatly improve the manuscript.

Funding

The study was financially supported by the Shaoguan University key research project (grant no. SZ2016KJ02) and the China Scholarship Council (grant no. 201708440546).

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  1. School of Chemistry and Civil Engineering, Shaoguan University, Shaoguan, 512005, China

    Weidong Lu

  2. Department of Paper and Bioprocess Engineering, SUNY College of Environmental Science and Forestry, 1 Forestry Drive, Syracuse, NY, 13210, USA

    Weidong Lu & Shijie Liu

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Lu, W., Liu, S. Choline chloride–based deep eutectic solvents (Ch-DESs) as promising green solvents for phenolic compounds extraction from bioresources: state-of-the-art, prospects, and challenges. Biomass Conv. Bioref. 12, 2949–2962 (2022). https://doi.org/10.1007/s13399-020-00753-7

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