Skip to main content

Advertisement

Log in

Evaluation of Lateral Temporal Bone Resection in Locally Advanced Tumours of the Parotid Gland

  • Original Article
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

This study evaluated the effects of lateral temporal bone resection (LTBR) on local tumour control in patients with locally advanced parotid gland tumours. The medical records of seven patients treated with radical parotidectomy combined with LTBR for locally advanced primary parotid tumour at the Otolaryngology Department of Dokuz Eylul University between January 1995 and December 2016 were retrospectively evaluated. Demographic variables, tumour characteristics, treatment properties, postoperative complications, follow-up durations and local, regional and distant recurrences were analysed. Before referral to our clinic, four patients had de novo primary parotid tumours, and three patients had a recurrence of primary parotid tumours. The histopathologic diagnoses were squamous cell carcinoma in two patients, and adenosquamous carcinoma, malignant myoepithelial carcinoma, adenocarcinoma, adenoid cystic carcinoma and spindle cell sarcoma in the other patients. During the follow-up period, one patient died due to postoperative pulmonary embolism in the first month, and four patients died due to distant metastasis without local or regional recurrences. LTBR combined with radical parotidectomy in locally advanced primary malignant parotid gland tumours is a feasible surgical technique for local tumour control. However, the most common cause of death in these cases is distant metastases, despite appropriate resection.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Gidley PW, Thompson CR, Roberts DB, Weber RS (2011) The results of temporal bone surgery for advanced or recurrent tumors of the parotid gland. Laryngoscope 121(8):1702–1707. https://doi.org/10.1002/lary.21867

    Article  PubMed  Google Scholar 

  2. Gidley PW, DeMonte F (2013) Temporal bone malignancies. Neurosurg Clin N Am 24(1):97–110. https://doi.org/10.1016/j.nec.2012.08.009

    Article  PubMed  Google Scholar 

  3. Mehra S, Morris LG, Shah J, Bilsky M, Selesnick S, Kraus DH (2011) Outcomes of temporal bone resection for locally advanced parotid cancer. Skull Base 21(6):389–396. https://doi.org/10.1055/s-0031-1287682

    Article  PubMed  PubMed Central  Google Scholar 

  4. Kane WJ, McCaffrey TV, Olsen KD, Lewis JE (1991) Primary parotid malignancies. A clinical and pathologic review. Arch Otolaryngol Head Neck Surg 117(3):307–315. https://doi.org/10.1001/archotol.1991.01870150075010

    Article  CAS  PubMed  Google Scholar 

  5. Reddy SP, Marks JE (1988) Treatment of locally advanced, high-grade, malignant tumors of major salivary glands. Laryngoscope 98(4):450–454. https://doi.org/10.1288/00005537-198804000-00019

    Article  CAS  PubMed  Google Scholar 

  6. Nagliati M, Bolner A, Vanoni V, Tomio L, Lay G, Murtas R, Deidda MA, Madeddu A, Delmastro E, Verna R, Gabriele P, Amichetti M (2009) Surgery and radiotherapy in the treatment of malignant parotid tumors: a retrospective multicenter study. Tumori 95(4):442–448. https://pdfs.semanticscholar.org/8316/18f829e14183d530b245f43a8ce49cd0e313.pdf

    Article  PubMed  Google Scholar 

  7. Terhaard CHJ, Lubsen H, Rasch CRN, Levendag PC, Kaanders HHÀM, Tjho-Heslinga RE, van Den Ende PLA, Burlage F (2005) The role of radiotherapy in the treatment of malignant salivary gland tumors. Int J Radiat Oncol Biol Phys 61(1):103–111. https://doi.org/10.1016/j.ijrobp.2004.03.018

    Article  PubMed  Google Scholar 

  8. Bell RB, Dierks EJ, Homer L, Potter BE (2005) Management and outcome of patients with malignant salivary gland tumors. J Oral Maxillofac Surg 63(7):917–928. https://doi.org/10.1016/j.joms.2005.03.006

    Article  PubMed  Google Scholar 

  9. Byrne MN, Spector JG (1988) Parotid masses: evaluation, analysis, and current management. Laryngoscope 98(1):99–105. https://doi.org/10.1288/00005537-198801000-00020

    Article  CAS  PubMed  Google Scholar 

  10. Zbären P, Schüpbach J, Nuyens M, Stauffer E, Greiner R, Häusler R (2003) Carcinoma of the parotid gland. Am J Surg 186(1):57–62. https://doi.org/10.1016/S0002-9610(03)00105-3

    Article  PubMed  Google Scholar 

  11. Magnano M, Gervasio CF, Cravero L, Machetta G, Lerda W, Beltramo G, Orecchia R, Ragona R, Bussi M (1999) Treatment of malignant neoplasms of the parotid gland. Otolaryngol Head Neck Surg 121(5):627–632. https://doi.org/10.1016/S0194-5998(99)70070-7

    Article  CAS  PubMed  Google Scholar 

  12. Sullivan MJ, Breslin K, McClatchey KD, Ho L, Farrior EH, Krause CJ (1987) Malignant parotid gland tumors: a retrospective study. Otolaryngol Head Neck Surg 97(6):529–533. https://doi.org/10.1177/019459988709700603

    Article  CAS  PubMed  Google Scholar 

  13. Mantravadi AV, Marzo SJ, Leonetti JP, Fargo KN, Carter MS (2011) Lateral temporal bone and parotid malignancy with facial nerve involvement. Otolaryngol Head Neck Surg 144(3):395–401. https://doi.org/10.1177/0194599810393880

    Article  PubMed  Google Scholar 

  14. Shao A, Wong DK, McIvor NP, Mylnarek AM, Chaplin JM, Izzard ME, Patel RS, Morton RP (2013) Parotid metastatic disease from cutaneous squamous cell carcinoma: prognostic role of facial nerve sacrifice, lateral temporal bone resection, immune status and P-stage. Head Neck 36(4):545–550. https://doi.org/10.1002/hed.23323

    Article  PubMed  Google Scholar 

  15. Bacciu A, Clemente IA, Piccirillo E, Ferrari S, Sanna M (2013) Guidelines for treating temporal bone carcinoma based on long-term outcomes. Otol Neurotol 34(5):898–907. https://doi.org/10.1097/MAO.0b013e318281e0a9

    Article  PubMed  Google Scholar 

  16. Parsons H, Lewis JS (1954) Subtotal resection of the temporal bone for cancer of the ear. Cancer 7(5):995–1001. https://doi.org/10.1002/1097-0142(195409)7:5%3C995:AID-CNCR2820070524%3E3.0.CO;2-A

    Article  CAS  PubMed  Google Scholar 

  17. Conley JJ, Novack AJ (1960) The surgical treatment of malignant tumors of the ear and temporal bone. Part 1. AMA Arch Otolaryngol 71:635–652

    Article  CAS  PubMed  Google Scholar 

  18. Lee S, Kim GE, Park CS, Choi EC, Yang WI, Lee CG, Keum KC, Kim YB, Suh CO (2001) Primary squamous cell carcinoma of the parotid gland. Am J Otolaryngol 22(6):400–406. https://doi.org/10.1053/ajot.2001.28068

    Article  CAS  PubMed  Google Scholar 

  19. Gaughan RK, Olsen KD, Lewis JE (1992) Primary squamous cell carcinoma of the parotid gland. Arch Otolaryngol Head Neck Surg 118(8):798–801. https://doi.org/10.1001/archotol.1992.01880080020006

    Article  CAS  PubMed  Google Scholar 

  20. Sterman BM, Kraus DH, Sebek BA, Tucker HM (1990) Primary squamous cell carcinoma of the parotid gland. Laryngoscope 100(2):146–148

    Article  CAS  PubMed  Google Scholar 

  21. Shemen LJ, Huvos AG, Spiro RH (1987) Squamous cell carcinoma of salivary gland origin. Head Neck Surg 9(4):235–240. https://doi.org/10.1002/hed.2890090407

    Article  CAS  PubMed  Google Scholar 

  22. Cerda T, Sun XS, Vignot S, Marcy PY, Baujat B, Baglin AC, Ali AM, Testelin S, Reyt E, Janot F, Thariat J (2014) A rationale for chemoradiation (vs radiotherapy) in salivary gland cancers? On behalf of the REFCOR (French rare head and neck cancer network). Crit Rev Oncol Hematol 91(2):142–158. https://doi.org/10.1016/j.critrevonc.2014.02.002

    Article  PubMed  Google Scholar 

  23. Nutting CM, Rowbottom CG, Cosgrove VP, Henk JM, Dearnaley DP, Robinson MH, Conway J, Webb S (2001) Optimisation of radiotherapy for carcinoma of the parotid gland: a comparison of conventional, three-dimensional conformal, and intensity-modulated techniques. Radiother Oncol 60(2):163–172. https://doi.org/10.1016/S0167-8140(01)00339-5

    Article  CAS  PubMed  Google Scholar 

Download references

Funding

There is not any funding organisations to be disclosed for the present study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mustafa Aslıer.

Ethics declarations

Conflict of interest

The authors have no funding, financial relationships or conflict of interest to disclose.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Aslıer, M., Doğan, E., İkiz, A.Ö. et al. Evaluation of Lateral Temporal Bone Resection in Locally Advanced Tumours of the Parotid Gland. Indian J Otolaryngol Head Neck Surg 71 (Suppl 2), 1402–1407 (2019). https://doi.org/10.1007/s12070-018-1483-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-018-1483-4

Keywords

Navigation