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Biosynthesis of Zinc Oxide Nanoparticles Using Bacillus Species Potentiates Anticancer and Antimicrobial Activity

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Biosynthesis of Zinc Oxide Nanoparticles Using Bacillus Species Potentiates Anticancer and Antimicrobial Activity


Hanumitha. S | Mahalakshmi. V | Abirami. S

https://doi.org/10.31142/ijtsrd17137



Hanumitha. S | Mahalakshmi. V | Abirami. S "Biosynthesis of Zinc Oxide Nanoparticles Using Bacillus Species Potentiates Anticancer and Antimicrobial Activity" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-5, August 2018, pp.1796-1802, URL: https://www.ijtsrd.com/papers/ijtsrd17137.pdf

The biological methods for synthesis of nanoparticles by using various microorganisms, enzymes, plants, and their extracts have been suggested as the probable and promising eco friendly alternatives to the chemical and physical methods of synthesis. The biocompatibility of nanoparticles is more essential for specific biomedical applications and researches. The aim of this study was to evaluate the effect of ZnO nano particles for anticancer and antimicrobial activity. In this study ZnO Nano particles were synthesized by Bacillussubtilisusing Zinc acetate dihydrate as substrate and sodium borohydride as reducing agent. The preliminary confirmation of the presence of the nanoparticles was the formation of precipitate and white coloration in the final mixture. The confirmation of the presence of nanoparticles was carried out by SEM analysis. The antimicrobial activity of nanoparticles was determined by well diffusion method and also the synergistic effect of nanoparticles with antibiotics on bacteria was determined by well diffusion method. The anticancer activity of the nanoparticles on MDA MB321 (human breast cancer cells) was determined by MTT assay.

Nanoparticles, anticancer, antimicrobial.


IJTSRD17137
Volume-2 | Issue-5, August 2018
1796-1802
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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