Morphological spectrum of salivary gland tumors withspecial reference to mucin stains

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Original Article

Author Details : Faeeza Begum*, Shaista Choudhary

Volume : 6, Issue : 4, Year : 2021

Article Page : 267-271

https://doi.org/10.18231/j.jdpo.2021.057

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Abstract

Background: Salivary gland neoplasm are rare and constitute about 3% of all head and neck neoplasms. Mucins are altered in pathological states and are stained by special stains like Periodic Acid Schiff, Alcian Blue and Mucicarmine.
Objectives: To study the histomorphology of resected salivary gland tumors and mucin staining pattern wherever indicated.
Materials and Methods: Surgically resected specimens received at our tertiary care hospital and subjected to histopathological examination. Specimens were fixed in 10% formalin, processed and embedded in paraffin blocks, serially cut to get sections of 3-5 microns thickness. Stained with hematoxylin and eosin for all. Mucin stains were used wherever applicable.
Results: Total number of cases studied were 70. Out of which 46 were benign (65.7%) and 24 were malignant (34.3%). Among benign tumours, Pleomorphic adenoma was the commonest tumour (48.57), followed by Warthin tumor (7.14%), Basal cell adenoma (4.28%), Myoepithelioma (1.43%), Oncocytoma (1.43%), Hemangioma (1.43%), Sailolipoma (1.43%). The Mucoepidermoid carcinoma was the most common malignant tumor (17.14%) followed by Adenoid cystic carcinoma (5.71%), Acinic cell carcinoma (4.28%), Polymorphous adenocarcinoma (1.43%), Epithelial myoepithelial carcinoma, Squamous cell carcinoma (1.43%), Salioblastoma (1.43%), Lymphoma (1.43%). Parotid was most common site for both benign and malignant tumor. Females are affected more commonly than males. Mucin staining pattern was noted.
Conclusion: Salivary gland tumors have complex range of morphological spectrum. Histopathological examination is the golden standard for diagnosis and mucin stain would add as an adjunct to the diagnosis.
 
Keywords: Salivary gland, Benign, Malignant, Pleomorphic adenoma, Mucin, Mucoepidermoid carcinoma

How to cite : Begum F, Choudhary S, Morphological spectrum of salivary gland tumors withspecial reference to mucin stains. IP J Diagn Pathol Oncol 2021;6(4):267-271

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